Smart building uses technology to deliver useful and consistent experiences in performances, services and system. Due to climate change and pandemic situation, the implementation of smart building will be important to deliver sustainability in terms of energy efficiency and wellbeing. The purpose of the study is to know how critical of smart design through integrated approach to achieve sustainable performance in building life cycle. Smart lighting design in the office building is the focus of the study. The research method was using qualitative method with a case study approach on the building that has been certified under Greenship New Building 1.2. Smart design through sustainable design approach itself shall consist of these four design tiers: 1) base building design; 2) passive system; 3) active system; and 4) smart building application. According to the study, the result shows how critical the integration among the design tiers by considering energy efficiency and wellbeing to deliver smart lighting system design. Moreover, it can be said that multidiscipline collaboration on design process is a necessary.